Hereditary angioedema and pregnancy

Abstract

Hereditary angioedema is a rare genetic disease presenting in one out of every 50 000 individuals. The condition is characterized by episodes of subcutaneous and submucosal edema. Hormonal alterations may trigger a crisis and pregnancy affects the number of seizures. Two clinical cases are presented of pregnant women with a personal history of hereditary angioedema who had crises during pregnancy, delivery and puerperium, followed by satisfactory evolution. A review was conducted about the topic.