Pregnant with Kikuchi Fujimoto disease

Abstract

Introduction: Kikuchi Fujimoto disease or necrotizing histiocytic lymphadenitis without granulocytic infiltration was first described in 1972. Rare and benign disease, characterized by frequently growth of painful cervical lymph nodes, fever, night sweats and general malaise.
Objective: To present the evolution of a pregnant woman with Kikuchi Fujimoto disease.
Case report: We communicate herein a case of a 26-year-old, white skin color pregnant woman, from Boyeros municipality in Havana. She was diagnosed three years ago with Kikuchi Fujimoto disease at Hermanos Ameijeiras Clinical Surgical Hospital in Havana, Cuba. Her pregnancy follow-up was carried out at Ramón González Coro Gyneco-obstetric Teaching Hospital in Havana. Her obstetric history is G1 P0 A0. Her last menstrual period was dated January 23, 2019. She had a history a prolonged pregnancy-induced eutocic delivery with 41.3 week gestational age. It was classified as a risk pregnancy and close monitoring of the maternal and fetal well-being was maintained during pregnancy, childbirth and the puerperium, as it was a pregnant woman with Kikuchi Fujimoto disease, which is rare in our setting. She evolved up to 45 days postpartum, without complications.
Conclusions: The evolution of this case confirms the benign and self-limited nature of this little-known, infrequent and little-documented disease, especially in pregnant women. Hence the importance of adequate differential diagnosis, particularly since it can be confused with neoplastic and reactive processes. The evolution of this pregnancy, with continuous and multidisciplinary care, allowed a satisfactory maternal and fetal outcome until a dystocic delivery was achieved, by cesarean section at 41.3 weeks of gestation.