Non Neoplastic Findings and Epithelial Cell Abnormalities in Cervical Cytology

Abstract

Introduction: The Pap test aims at diagnosing precancerous or cancerous lesions of the cervix, hormonal evaluation, and bacterial flora.
Objectives: Determine the proportion of non-neoplastic findings, squamous and glandular epithelial abnormalities referred to the district ofHospital Nacional Docente Madre Niño San Bartolome.
Methods: A prospective, analytical, correlational, cross-sectional research was designedfor all vaginal smear which were referred from five health networks and micro-networks. Cytological processing was carried out in accordance with applicable international requirements. Cytologic interpretation was performed according to Bethesda System.
Results: Out of 72,644 cervical smears evaluated by Bethesda quality system, the proportion of results with cervical uterine disorders (prevalence 6.5 % CI 95 %: 6.32 %, 6.68 %) were 4724 (6.5 %) samples, negative posevaluación was 35318 (51.7 %) samples, and nonneoplastic findings 32 602 (48.2 %) samples, (p< 0.005). Posttest probability was 89.3 % (CI 95 %: 87.1 % to 91.1 %; likelihood ratio LR > 10) and a significant direct correlation was established between the findings/nLiM and ages of patients (rho= 0.477; p< 0.005). Moreover, 46.53 % of NIM flora suggestive corresponds to bacterial vaginosis (BV), 22.5 % to reactive changes associated with inflammation and squamous metaplasia 21 % (MET). The most frequent association was MET, VB, and severe inflammation 5.5 % (1495 results).
Conclusions: The proportion of non-neoplastic findings was considerable; squamous and glandular epithelial abnormalities were above average standard.