Immune-Pathogenesis of Pregnant Hypertension

Abstract

Pregnant hypertension is a frequent pregnancy disorder. Researchers has recentely advanced in understanding this disease pathogenesis. The immune system plays a key role in this disease onset. Decidual natural killer cells are fundamental component in vascular remodeling during placental development. When alterations occurs in this cell population, placental ischemia is induced promoting the release of vascular factors and inflammation mechanisms that cause these disease symptoms.